| Acronym | Definition |
|---|
| SPACE | School of Professional and Continuing Education |
| SPACE | Spurring Private Aerospace Competitiveness and Entrepreneurship Act of 2015 |
| SPACE | Search Project for Aspects of Close Encounters (est. 1992; New York) |
| SPACE | Semantics, Program Analysis, and Computing Environments for Memory Management (Workshop) |
| SPACE | Sentient Protoplasm against Colonial Encroachment |
| SPACE | Sustaining Privacy in Autonomous Collaborative Environments (International Workshop) |
| SPACE | Sort, Purge, Assign a Home, Containerize, Equalize (clutter elimination) |
| SPACE | Sand Point Arts & Cultural Exchange (Seattle, WA) |
| SPACE | Sustainable Practices in Agriculture for Critical Environments |
| SPACE | Spacecraft Prelaunch Automatic Checkout Equipment |
| SPACE | Software Product Advanced Certification and Evaluation |
| SPACE | Satellite Precipitation and Cloud Experiment |
| SPACE | Students Participating Actively in County Education (Virginia) |
| SPACE | Students Pursuing Academics and Careers in Engineering (University of Pittsburgh) |
| SPACE | Sports, Performing Arts & Creative Education (African Centre for Human Development & Social Change; Ghana) |
| SPACE | Serratia, Pseudomonas, Acinetobacter, Citrobacter, Enterobacter |
| SPACE | Short Professional and Continuing Education |