| Acronym | Definition |
|---|
| RUP | Rational Unified Process (software engineering process) |
| RUP | Rupee (currency) |
| RUP | Rumen Undegradable Protein |
| RUP | Repeat Use Procedure |
| RUP | Runner Up (competition) |
| RUP | Rollup Patch |
| RUP | Retail Update |
| RUP | Rational Unified Process |
| RUP | Restricted Use Pesticide |
| RUP | Raza Unida Party (est. 1970) |
| RUP | Rice University Press (Houston, TX) |
| RUP | Roaming User Profile (computer synchronization) |
| RUP | Real Ultimate Power |
| RUP | Reconnaissance d'Utilité Publique (French: Recognition of Public Interest) |
| RUP | Ready Up (computer gaming) |
| RUP | Responsible Use Policy |
| RUP | Remote Uptime |
| RUP | Rural/Urban Projection |
| RUP | Routing Update Protocol |
| RUP | Reitaku University Press (Reitaku University; Kashiwa, Chiba Prefecture, Japan) |