| Acronym | Definition |
|---|
| SCALE | Southern California Linux Expo |
| SCALE | Student Coalition for Action in Literacy Education |
| SCALE | Servants of Creatures Arriving Late to Earth (Godzilla) |
| SCALE | Standardized Computer Analyses for Licensing Evaluation |
| SCALE | Secondary Collegiate Articulated Learning Experience |
| SCALE | South Carolina Association of Law Enforcement Explorers |
| SCALE | Shuttle Coherent Atmospheric LIDAR Experiment (NASA) |
| SCALE | Short-term Commitment and Long-term Estimate |
| SCALE | System Characteristics and Assurance Level Evaluation (IEEE) |
| SCALE | Sustainable Community based Approaches for Livelihoods Enhancement (India) |
| SCALE | Specialization in Culture and Language Education |