| Acronym | Definition |
|---|
| SPFA | Shortest Path Faster Algorithm (graphs) |
| SPFA | Spray Polyurethane Foam Alliance (trade organization) |
| SPFA | Syndicat des Producteurs de Films d'Animation (French film producers association) |
| SPFA | Steel Plate Fabricators Association (Geneva, Illinois) |
| SPFA | Single Point Failure Analysis |
| SPFA | Solidarite Protestante France-Armenie (French: Protestant Solidarity France-Armenia) |
| SPFA | Fireman Apprentice, Steam Propulsionman Striker (USN rating) |
| SPFA | Single Parent Family Association Inc. (Baulkham Hills, New South Wales, Australia) |