SPFC
| Acronym | Definition |
|---|---|
| SPFC | Sao Paulo Futebol Clube |
| SPFC | Special Purpose Function Code |
| SPFC | Server Pages Foundation Classes |
| SPFC | Smashing Pumpkins Fan Collaborative |
| SPFC | Solid Polymer Fuel Cell |
| SPFC | Student Parabolic Flight Campaign (European Space Agency) |
| SPFC | Southern Pacific Funding Corporation (investing) |
| SPFC | Spastic paretic facial contracture |