| Acronym | Definition |
|---|
| USR | Ufficio Scolastico Regionale (Italian: Regional Office of Education) |
| USR | U.S. Robotics |
| USR | Unix System Resources |
| USR | Upper Saddle River (New Jersey) |
| USR | Ultimate Software Radio |
| USR | Us Robotics |
| USR | User Service Request |
| USR | Unix Directory Structure |
| USR | Unix System Resource |
| USR | Unit Status Report |
| USR | Urban Search and Rescue |
| USR | Ufficio Studi e Ricerche (Italian: Office of Studies and Research; Canton Ticino, Switzerland) |
| USR | User Support Room (US NASA) |
| USR | Usui System of Reiki (natural healing) |
| USR | Upwelling Solar Radiation (meteorology) |
| USR | Universities Statistical Record |
| USR | Universal Sporting Rifle (Steyr) |
| USR | Universal Space Rectangular |
| USR | Up Stage Right |
| USR | Unité de Secours Régional (French: Regional Emergency Unit; Switzerland) |
| USR | Unit Safety Representative |
| USR | Uniunii Studentilor Din România (Romania) |
| USR | Upstream Ready |
| USR | Unsatisfactory Service Report |