| Acronym | Definition |
|---|
| VU | Volume Unit |
| VU | View |
| VU | Vanuatu (ISO country code, top level domain) |
| VU | Virtual University |
| VU | Vrije Universiteit Amsterdam (University of Amsterdam; Netherlands) |
| VU | Very Useful |
| VU | Vulnerable (IUCN Red List of Threatened Species category) |
| VU | Vincennes University |
| VU | Vanderbilt University |
| VU | Velvet Underground (band) |
| VU | Victoria University (Victoria, Australia) |
| VU | Vilnius University (Lithuania) |
| VU | Valparaiso University |
| VU | Vanguard University (Southern California) |
| VU | Villanova University |
| VU | Vivendi Universal (media and telecommunications company) |
| VU | Véhicules Utilitaires (French: Commercial Vehicles) |
| VU | Video Update (Video Store) |
| VU | VHF/UHF |
| VU | Vehicle Unit |
| VU | Venstres Ungdom (Denmark) |
| VU | Volksunie (Flemish Political Party) |
| VU | Vaterländische Union (German: Fatherland Union, Liechtenstein) |
| VU | Vector Units |
| VU | Viribus Unitis (battleship) |
| VU | Utility Squadron (US Navy aviation unit designation used from 1946 to 1965) |
| VU | Visitor Use (various organizations) |
| VU | Vukovar, Croatia (license plate) |
| VU | Voice Unit |
| VU | Vehicle Utility |
| VU | Utility Speed |
| VU | Veeder Units (nuclear control rod position) |
| VU | Versorgungs-Unteroffizier |