| Acronym | Definition |
|---|
| DHU | DirectX Happy Uninstall (software) |
| DHU | Départements Hospitalo-Universitaires (French: University Hospital Departments) |
| DHU | Dark Horse United (gaming clan) |
| DHU | Direction de l'Hydraulique Urbaine (French: Directorate of Urban Water; Sénégal) |
| DHU | Data Handling Unit |
| DHU | Dansk Hockey Union |
| DHU | Deutsche Homoeopathische Union (German Homoeopathic Union) |
| DHU | Don't Hang Up |
| DHU | Developers Hate You (Facebook application) |
| DHU | Deck Hand Uncertified (ship deck worker with experience but no certificates) |
| DHU | Detector Head Unit |