| Acronym | Definition |
|---|
| GCD | Greatest Common Divisor |
| GCD | Grand Central Dispatch (Apple technology) |
| GCD | Griffith College Dublin (Dublin, Ireland) |
| GCD | Greatest Common Denominator |
| GCD | Game Compact Disc |
| GCD | Group Creative Director (various organizations) |
| GCD | Grand Comic-Book Database |
| GCD | groundwater conservation district |
| GCD | Global Cooldown (gaming) |
| GCD | Gestionnaire du Commerce de Détail (French: Retail Trade Manager; Switzerland) |
| GCD | Grand Coulee Dam |
| GCD | General Commercial District (various locations) |
| GCD | Gulf Coast Division (Orange, TX) |
| GCD | Gas Chromatography Distillation |
| GCD | Gestion des Clients de la Douane (French: Management of Customs Clients; Switzerland) |
| GCD | Glen Canyon Dam |
| GCD | General and Complete Disarmament |
| GCD | General Conformity Determination |
| GCD | Gold Coast Desalination (plant) |
| GCD | Global Clinical Development |
| GCD | Greater Confinement Disposal (waste management) |
| GCD | Genome Cluster Database (sequence family analysis platform) |
| GCD | Global Communication Devices |
| GCD | Gaia Community Discussion |
| GCD | Guild of Catholic Doctors |
| GCD | Global Clan Directory (gaming) |
| GCD | Genetic Chromosome Dissection |
| GCD | Global Connectivity Demonstration |
| GCD | Goals of Care Designation |
| GCD | General Defense Position/Plan |
| GCD | Glass Cutting Device |
| GCD | Generator Control Display |
| GCD | Global Column Decoder (computer memory) |