| Acronym | Definition |
|---|
| PRB | Problem |
| PRB | Population Reference Bureau (think tank) |
| PRB | Powder River Basin (Wyoming) |
| PRB | Pearl River Bridge (Chinese food) |
| PRB | Paso Robles (California) |
| PRB | Permeable Reactive Barrier (groundwater treatment technology) |
| PRB | Preliminary Review Board |
| PRB | Program Request Block |
| PRB | Physical Review B (American Physical Society journal of condensed matter and material physics) |
| PRB | Retinoblastoma Gene Product |
| PRB | Pre-Raphaelite Brotherhood |
| PRB | Program Review Board (US DoD; Military Health System) |
| PRB | Pseudo-Random Binary |
| PRB | Performance Review Board |
| PRB | Publications Review Board (US CIA) |
| PRB | Parks and Recreation Board (various locations) |
| PRB | Professional Responsibility Board (Vermont) |
| PRB | Project Review Board |
| PRB | Packet Receive Buffer |
| PRB | Pangani River Basin (Tanzania) |
| PRB | Panel Review Board |
| PRB | Proposal Review Board (various organizations) |
| PRB | Renaissance Party du Benin (Benin) |
| PRB | Peer Review Board (scholarly organizations) |
| PRB | Pre-Retcon Beyonder (Marvel Comics) |
| PRB | Problem Review Board |
| PRB | Pelton Round Butte (hydroelectric project; Oregon) |
| PRB | Public Reference Branch (US SEC) |
| PRB | Procurement Review Board |
| PRB | Policy Review Board |
| PRB | Package Responsible Buyer |
| PRB | Partai Rakyat Brunei (Brunei People's Party) |
| PRB | Physical Resource Block (telecommunications) |
| PRB | People's Republic of Bulgaria |
| PRB | Prayer Request Board |
| PRB | Personnel Replacement Battalion |
| PRB | FCC Private Radio Bureau |
| PRB | Procedure Review Board |
| PRB | Payload Reference Bench |
| PRB | Problem Reporting Bulletin |
| PRB | People's Republic of Berkeley (humor) |
| PRB | Peoria-Rockford Bus Company |
| PRB | Propeller Bulletin |
| PRB | Partners in Revitalization and Building |
| PRB | Planetary Robotics Building (Carnegie Mellon University) |
| PRB | Program Resources Branch (Canada) |
| PRB | Pet Returnable Bottle (packaging) |
| PRB | Proofreading Box |