PUO
| Acronym | Definition |
|---|---|
| PUO | Prohibited User Operation |
| PUO | Pyrexia of Unknown Origin |
| PUO | Plutonium Oxide |
| PUO | Politeknik Ungku Omar (Malaysia) |
| PUO | Prohibited User Operation (DVD) |
| PUO | Princeton University Orchestra |
| PUO | Portepee Unteroffizier (German military) |